Most people are already aware that green tea is good for you, with the added bonus of also tasting good, but some of this super leaf’s properties might be more beneficial than once perceived. EGCG (Epigallocatechin-3-gallate), a key active ingredient in the green tea leaf is shaping up to be this aformentioned beneficial property, lending its tumor fighting capabilities to the treatment of bladder cancer.
As of 2017, estimates have shown that the rates of new bladder cancers and of cancer deaths have been declining slightly from past years, but it is still predicted that 79,030 new cases of bladder cancer will be diagnosed and that 16,870 deaths from this cancer will occur this year in the United States alone (stats pulled from the American Cancer Society). Stats like these make the research being done at Loudi Central Hospital and at the Xiangya School of Medicine, Central South University in China all the more important. The research suggests that the intake of EGCG may be a well-suited approach towards bladder cancer treatment by regulating autophagy pathway (autophagy is commonly activated by nutrient deprivation but is also associated with cancer). To aid in clarifying whether EGCG caused autophagosome formation, Delong America’s LVEM5 electron microscope was put to use in its conventionally used TEM mode. In this case, the low-voltage of the LVEM5 benchtop microscope helped maintain sample deterioration to a bare minimum while providing high contrast images of preferred areas of interest.
In the end, results from data gathered proved to be conclusive that EGCG did in fact exhibit an inhibitory effect on bladder cancer, thus making the activity of consuming green tea on a regular basis a proper bladder cancer preventative measure.
Inhibitory effect of epigallocatechin-3-gallate on bladder cancer cells via autophagy pathway
Liao H.1, Xiao Y.2, Hu Y.3, Xiao Y.1, Yin Z.1, Liu L.4, Kang X.1, Chen Y.1 (2016)
-Departments of 1Urology, 2Orthopedics, 4Oncology, Loudi Central Hospital of Hunan Province, Loudi, China
3: Department of Colorectal Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, China
International Journal of Clinical and Experimental Medecine, (9)6, 9868-9878. ISSN:1940-5901/IJCEM0024398